Formulation science
Formulation Science.
Designed for You.
CBDAe
Cannabidiolic Acid Methyl Ester
What is CBDAe?
A cannabinoid-derived cosmetic ingredient created through a proprietary stabilisation process, and selected for its suitability in skin-contact formulations.
Why CBDAe?
It represents an innovation in formulation science — a next-generation botanical ingredient chosen for stability, purity and sensory comfort.
The patent story
A proprietary method developed through years of pharmaceutical R&D experience, ensuring CBDAe remains stable and effective in a cosmetic formulation.
Go deeper into the science.
For the curious: more on the biology, the chemistry, and the story behind CLEIR.
The Endocannabinoid System, Explained
A plain-English introduction to the body system CBDA interacts with, and why researchers are paying attention to it.
Read the article →CBDAe vs CBD: What's the Difference?
Why we chose a stabilised ester of CBDA over standard CBD, and what that means for a wearable product.
Read the article →A History of Botanicals, From Ancient Remedies to Modern Science
How hemp and plant-based ingredients went from folk tradition to laboratory-grade formulation.
Read the article →Sixty years of pharmaceutical R&D. One patented breakthrough.
CLEIR was founded by Dr Lee Proctor and Colin Leece, who bring decades of combined experience in pharmaceutical science, research and development. Their work has consistently sat at the intersection of chemistry, process design and scalable manufacturing, developing and patenting technologies for formulation problems others had set aside. That expertise is what made CBDAe possible: a patented, gentle esterification process built specifically to stabilise CBDA for real-world, skin-contact formulation.
60+
Years combined pharmaceutical R&D
1
Patented esterification technology
100%
Cosmetic-compliant formulation
Dr Lee Proctor
Co-Founder, Organic Chemistry
Colin Leece
Co-Founder, Formulation & Manufacturing
Botanical & mineral actives
Vanillyl Butyl Ether
Vanillyl Butyl Ether
A botanical-derived agent that creates the gentle warmth sensation at the skin’s surface.
Vanillyl Butyl Ether
Vanillyl Butyl Ether
Our formulation principles
Purity
Stability
A patented process keeps CBDAe stable and effective in cosmetic form.